Pretibial Myxœdema

Localized Pretibial 'Myxœdema' in Thyrotoxicosis

a localized pretibial accumulation of mucin under the skin is not found in myxcedema, but for want of a proper name and in order to facilitate reference to earlier literature, the name has been retained. It has been suggested by Webber (1937) that the word myxcedema should be in inverted commas. Trotter and Eden (1942) have recently reviewed 73 cases of this condition mentioned in literature, a...

A Case of Myxœdema

noticed swelling of the legs, which graduall\T extended to the whole body. His speech became thick, and he found his memory getting weaker. State on admission.?Has a peculiar complexion, thick speech, and slow in movements. The whole body appears as if swollen. Hairs not affected. Bowels regular. Appetite good. All organs healthy. Sleeps with a very heavy snore. Urine flows freely. Sp. Gr. 1002...

Myxœdema with Ascites

Ascites has been noted occasionally in myxedema. Escamilla Lisser and Shephardson reported a case in 1935 and reviewed fifteen cases. Watson and others reported two cases in 1941. In other cases the clinical picture was like that of nephrosis, and response to thyroid therapy paralleled that first described by Epstein. Up to 1941, twenty-two well-established cases of myxcedema with ascites have ...

The Treatment of Myxœdema

Severe pretibial myxedema.

Although pretibial myxedema (PTM) occurs in 4.3% of patients with Graves's disease, the most severe variant, elephantiasis nostras verrucosa, is found in less than 1% of cases. The most frequent location of infiltration is the lower extremities, especially the pretibial areas and on the dorsum of the foot. The authors report one of the most severe cases of elephantiasis nostras verrucosa, follo...